Post-translational Modification of Protein Biopharmaceuticals

Friday, 13. August 2010

Product Description
From the leading author in the field, known around the world for his work and his authoritative publications, the contents of this book have been selected so as to reflect their relative importance for biopharmaceuticals. As a result, around half of the book is devoted to protein glycosylation, while the remainder is made up of other modifications, such as carboxylation, hydroxylation, sulfation, amidation and proteolytic processing. A final section addresses the latest trend of engineering the modification pattern to improve a given biopharmceutical, presenting several recent case studies of successful posttranslational engineering.
This first authoritative overview of the topic is an indispensable guide for drug developers and drug manufacturers with an interest in protein pharmaceuticals.

Post-translational Modification of Protein Biopharmaceuticals

Posttranslational Modification of Proteins: Expanding Nature’s Inventory

Thursday, 11. March 2010

Product Description
More than five percent of the genes in higher eukaryotic genomes encode enzymes that posttranslationally modify proteins, greatly expanding the complexity and diversity of proteomes. This book examines the molecular logic of the major types of covalent modifications of proteins and their biological consequences.

Posttranslational Modification of Proteins: Expanding Nature’s Inventory